• About Us
  • Our Contributors
  • Privacy Policy
  • Contact
Friday, July 18, 2025
  • Login
No Result
View All Result
FactFile
  • National
  • International
  • Economy
  • Health
  • Science
  • Sports
  • Tech
    Pixel 10 Launch Date Confirmed: Top Specs, Features & Android 15

    Pixel 10 Launch Date Confirmed: Top Specs, Features & Android 15

    Week Security Practices Behind Majority of 2024 Cyberattacks: Govt Advisory

    Weak Security Practices Behind Majority of 2024 Cyberattacks: Govt Advisory

    Meta Cracks Down on Unoriginal Content & Fake Accounts on Facebook

    Meta Cracks Down on Unoriginal Content & Fake Accounts on Facebook

    Apple iPhone 17 Lineup Launch Date, Expected Features: Details Inside

    Apple iPhone 17 Lineup Launch Date, Expected Features: Details Inside

    HMD and Nokia are Quitting Another Country

    HMD and Nokia are Quitting Another Country

    WhatsApp Solves Group Chat Mystery with THIS New Feature

    WhatsApp Solves Group Chat Mystery with THIS New Feature

  • Entertainment
    Anne Hathaway’s ‘Verity’ Gets New Release Date

    Anne Hathaway’s ‘Verity’ Gets New Release Date

    What happened to Shefali Jariwala?

    What happened to Shefali Jariwala?

    Diljit Dosanjh Unveils Trailer for ‘Sardaar Ji 3’ Featuring Hania Aamir

    Diljit Dosanjh Unveils Trailer for ‘Sardaar Ji 3’ Featuring Hania Aamir

    Are Ayeza Khan & Danish Taimoor Leaving Entertainment Industry?

    Are Ayeza Khan & Danish Taimoor Leaving Entertainment Industry?

    Saheefa Jabbar Faces Backlash Over Bold Social Media Posts

    Saheefa Jabbar Faces Backlash Over Bold Social Media Posts

    Faisalabad: TikToker Sana Yousaf's Alleged Killer Arrested

    Faisalabad: TikToker Sana Yousaf’s Alleged Killer Arrested

    Mahira Khan’s Pashto Song ‘Sada Ashna’ From Love Guru Goes Viral

    Mahira Khan’s Pashto Song ‘Sada Ashna’ From Love Guru Goes Viral

     ‘Son of Sardar’ Actor Mukul Dev Passes Away at 54

     ‘Son of Sardar’ Actor Mukul Dev Passes Away at 54

    All Pakistani Songs Removed from Spotify India: Here's Why!

    All Pakistani Songs Removed from Spotify India: Here’s Why!

  • Opinion
  • National
  • International
  • Economy
  • Health
  • Science
  • Sports
  • Tech
    Pixel 10 Launch Date Confirmed: Top Specs, Features & Android 15

    Pixel 10 Launch Date Confirmed: Top Specs, Features & Android 15

    Week Security Practices Behind Majority of 2024 Cyberattacks: Govt Advisory

    Weak Security Practices Behind Majority of 2024 Cyberattacks: Govt Advisory

    Meta Cracks Down on Unoriginal Content & Fake Accounts on Facebook

    Meta Cracks Down on Unoriginal Content & Fake Accounts on Facebook

    Apple iPhone 17 Lineup Launch Date, Expected Features: Details Inside

    Apple iPhone 17 Lineup Launch Date, Expected Features: Details Inside

    HMD and Nokia are Quitting Another Country

    HMD and Nokia are Quitting Another Country

    WhatsApp Solves Group Chat Mystery with THIS New Feature

    WhatsApp Solves Group Chat Mystery with THIS New Feature

  • Entertainment
    Anne Hathaway’s ‘Verity’ Gets New Release Date

    Anne Hathaway’s ‘Verity’ Gets New Release Date

    What happened to Shefali Jariwala?

    What happened to Shefali Jariwala?

    Diljit Dosanjh Unveils Trailer for ‘Sardaar Ji 3’ Featuring Hania Aamir

    Diljit Dosanjh Unveils Trailer for ‘Sardaar Ji 3’ Featuring Hania Aamir

    Are Ayeza Khan & Danish Taimoor Leaving Entertainment Industry?

    Are Ayeza Khan & Danish Taimoor Leaving Entertainment Industry?

    Saheefa Jabbar Faces Backlash Over Bold Social Media Posts

    Saheefa Jabbar Faces Backlash Over Bold Social Media Posts

    Faisalabad: TikToker Sana Yousaf's Alleged Killer Arrested

    Faisalabad: TikToker Sana Yousaf’s Alleged Killer Arrested

    Mahira Khan’s Pashto Song ‘Sada Ashna’ From Love Guru Goes Viral

    Mahira Khan’s Pashto Song ‘Sada Ashna’ From Love Guru Goes Viral

     ‘Son of Sardar’ Actor Mukul Dev Passes Away at 54

     ‘Son of Sardar’ Actor Mukul Dev Passes Away at 54

    All Pakistani Songs Removed from Spotify India: Here's Why!

    All Pakistani Songs Removed from Spotify India: Here’s Why!

  • Opinion
No Result
View All Result
FactFile
No Result
View All Result
Bluebird's $2.8 million gene therapy becomes most expensive drug after U.S. approval

Bluebird’s $2.8 million gene therapy becomes most expensive drug after U.S. approval

by Arshad Khan
August 18, 2022
in Health
0
Share on FacebookShare on TwitterLinkedIn Whatsapp

Bluebird has been in talks with insurers about a one-time payment option.

Bluebird’s $2.8 million gene therapy becomes most expensive drug after U.S. approval. The U.S. Food and Drug Administration on Wednesday approved bluebird bio’s (BLUE.O) gene therapy for patients with a rare disorder requiring regular blood transfusions, and the drugmaker priced it at a record $2.8 million.

The approval sent the company’s shares 8% higher and is for the treatment of beta-thalassemia, which causes an oxygen shortage in the body and often leads to liver and heart issues.

The sickest patients, estimated to be up to 1,500 in the United States, need blood transfusions every two to five weeks.

The therapy, to be branded as Zynteglo, is expected to face some resistance from insurers due to its steep price, analysts say.

More From FactFile: WHO Europe expects more monkeypox-related deaths

Gene therapies usually come with a high price tag as they are often curative and have faced hurdles in securing insurance coverage.

For instance, Novartis (NOVN.S) was in 2019 forced to offer discounts and work out “outcome-based” installments payments for its $2.1 million therapy Zolgensma after insurers balked at the drug’s price.

Bluebird has pitched Zynteglo as a potential one-time treatment that could do away with the need for transfusions, resulting in savings for patients over the long term.

The average cost of transfusions over the lifetime can be $6.4 million, Chief Operating Officer Tom Klima told Reuters before the approval. “We feel the prices we are considering still bring a significant value to patients.”

Bluebird has been in talks with insurers about a one-time payment option.

“Potentially, up to 80% of that payment will be reimbursed if a patient does not achieve transfusion independence, they (insure

rs) are very excited about that,” Klima said.

The FDA warned of a potential risk of blood cancer with the treatment but noted studies had no such cases.

Bluebird expects to start the treatment process for patients in the fourth quarter. No revenue is, however, expected from the therapy in 2022 as the treatment cycle would take an average of 70 to 90 days from initial cell collection to final transfusion.

Tags: NovartisTom KlimaU.S. Food and Drug AdministrationWHO
ShareTweetShareSend
Previous Post

Collingwood confident England can return fire at Lord’s

Next Post

Imran Khan asks ‘neutrals’ to review policies

Arshad Khan

Arshad Khan

Arshad Khan is a career journalist and working as reporter with Daily FactFile. He reports on versatile issues including government, politics and public issues. He also has interests in health and technology issues.

Related Posts

Loneliness & Social Isolation Linked to Higher Risk of Type 2 Diabetes, New Study Finds

Loneliness & Social Isolation Linked to Higher Risk of Type 2 Diabetes, New Study Finds

by Arshad Khan
July 16, 2025
0

Experts are calling for policy-level interventions to address the problem, especially in aging societies like Pakistan, where eldercare is underdeveloped....

Pakistani Doctors Perform First Successful Tummy Tuck Surgery

Pakistani Doctors Perform First Successful Tummy Tuck Surgery

by Arshad Khan
July 14, 2025
0

Tummy tuck surgery is normally only accessible in some big private hospitals in Karachi, said Dr. Roshan. Pakistani Doctors Perform...

MQM Founder Altaf Hussain Hospitalised in London Due to Illness

MQM Founder Altaf Hussain Hospitalised in London Due to Illness

by Arshad Khan
July 12, 2025
0

In addition to medication, Altaf Hussain has also received a blood transfusion. MQM Founder Altaf Hussain Hospitalised in London Due...

Punjab Bans Mobile Phone Use by Medical Staff During Duty Hours

Punjab Bans Mobile Phone Use by Medical Staff During Duty Hours

by Arshad Khan
July 7, 2025
0

Authorities have been directed to implement the ban without delay, ensuring full compliance at all levels. Punjab Bans Mobile Phone...

New Drug Turns Human Blood into Mosquito Killer

New Drug Turns Human Blood into Mosquito Killer

by Faiqa Chaudhary
July 7, 2025
0

In a remarkable breakthrough for public health, scientists have confirmed that a New Drug Turns Human Blood into Mosquito Killer,...

Australian Man Dies from ‘Extremely Rare’ Bat Bite Virus

Australian Man Dies from ‘Extremely Rare’ Bat Bite Virus

by Arshad Khan
July 5, 2025
0

Infected bats can transmit the virus to people, other bats and other mammals. Australian Man Dies from ‘Extremely Rare’ Bat...

Are Young Individuals Dying of Heart Attacks After Receiving COVID Vaccine During Pandemic?

Are Young Individuals Dying of Heart Attacks After Receiving COVID Vaccine During Pandemic?

by Arshad Khan
July 3, 2025
0

The viral stories being shared with claims of sudden deaths to COVID-19 vaccines is misleading and not supported by data....

Load More
Next Post
Imran Khan asks 'neutrals' to review policies

Imran Khan asks 'neutrals' to review policies

PSX loses 195 points, closes at 43,481.50 points

PSX loses 195 points, closes at 43,481.50 points

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

Facebook Twitter Youtube Instagram LinkedIn
FactFile

Newsletter

Subscribe to receive regular updates from FactFile.
SUBSCRIBE

Categories

  • Business
  • Economy
  • Education
  • Entertainment
  • FactFile
  • Fashion
  • Health
  • International
  • Interview
  • Lifestyle
  • National
  • News
  • Opinion
  • People
  • Science
  • Sports
  • Tech

Site Links

  • About Us
  • Our Contributors
  • Privacy Policy
  • Contact

© 2020-25 Daily FactFile

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Home
  • Business
  • Science
  • National
  • Entertainment
  • Sports
  • Fashion
  • Lifestyle
  • Tech
  • Health

© 2020-25 Daily FactFile